Article

Multi-organ functions of yolk sac during human early development

2022-08-05

Abstract excerpt

The yolk sac (YS) represents an evolutionarily-conserved extraembryonic structure that ensures timely delivery of nutritional support and oxygen to the developing embryo. However, the YS remains ill-defined in humans. We therefore assemble a complete single cell 3D map of human YS from 3-8 post conception weeks by integrating multiomic protein and gene expression data. We reveal the YS as a site of primitive and d...

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Literature Corpus work: 5c278beb-4b27-5b07-a4c5-feb5e56e7b44
DOI: 10.1101/2022.08.03.502475

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