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A distinct CD115 <sup>-</sup> erythro-myeloid precursor present at the maternal-embryonic interface and in the bone marrow of adult mice

2021-07-25

Abstract excerpt

During ontogeny, macrophages develop from CD115 + precursors, including erythro-myeloid progenitors (EMP). EMP arise in the embryonic yolk sac, the primary site of early haematopoiesis. In adults, CD115 + bone marrow-derived monocytes represent essential macrophage precursors. Herein, we identify a CD115 - macrophage precursor within the adult bone marrow that is unrelated to the classical monocyte lineage but...

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Literature Corpus work
d3d47d9b-3b1d-5388-9603-6b65ae7e0187
DOI
10.1101/2021.07.24.453629
Open publication

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A distinct CD115 <sup>-</sup> erythro-myeloid precursor present at the maternal-embryonic interface and in the bone marrow of adult miceDOI 10.1101/2021.07.24.453629
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