Development of a multi-locus CRISPR gene drive system in budding yeast

Abstract excerpt

<h4>ABSTRACT</h4> The discovery of CRISPR/Cas gene editing has allowed for major advances in many biomedical disciplines and basic research. One arrangement of this biotechnology, a nuclease-based gene drive, can rapidly deliver a genetic element through a given population and studies in fungi and metazoans have demonstrated the success of such a system. This methodology has the potential to control biological po...

Topics

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• Animals, Genetically Modified
• Clustered Regularly Interspaced Short Palindromic Repeats
• CRISPR-Cas Systems
• Diptera
• Gene Editing
• Phenotype
• RNA, Guide, CRISPR-Cas Systems
• Saccharomyces cerevisiae

Identifiers and source

Literature Corpus work

de67fe68-7c60-50a0-8a36-26abd9325061

DOI

10.1101/391334