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Article

Small-molecule control of super-Mendelian inheritance in gene drives

2019-06-14

Abstract excerpt

<h4>ABSTRACT</h4> By surpassing the 50% inheritance limit of Mendel’s law of independent assortment, CRISPR-based gene drives have the potential to fight vector-borne diseases or suppress crop pests. However, contemporary gene drives could spread unchecked, posing safety concerns that limit their use in both laboratory and field settings. Current technologies also lack chemical control strategies, which could be...

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Literature Corpus work
719b2e8b-4c44-5e59-966c-b65a18e02445
DOI
10.1101/665620
Open publication

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Small-molecule control of super-Mendelian inheritance in gene drivesDOI 10.1101/665620
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