Article

H3K4 di- and trimethylation modulate the stability of RNA polymerase II pausing

2022-11-29

Abstract excerpt

<h4>SUMMARY</h4> Modifications of histones are intricately linked with the regulation of gene expression, with demonstrated roles in various physiological processes and disease pathogenesis. Methylation of histone H3 lysine 4 (H3K4), implemented by the COMPASS family, is enriched at promoters and associated cis-regulatory elements, with H3K4 trimethylation (H3K4me3) considered a hallmark of active gene promoters....

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Literature Corpus work: ddf91a6e-a950-5054-bd00-b0ff1d823c84
DOI: 10.1101/2022.11.28.518073

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