Article

Respiratory viral infection promotes the awakening and outgrowth of dormant metastatic breast cancer cells in lungs

2024-04-05

Abstract excerpt

<title>Abstract</title> <p>Breast cancer is the second most common cancer globally. Most deaths from breast cancer are due to metastatic disease which often follows long periods of clinical dormancy<sup>1</sup>. Understanding the mechanisms that disrupt the quiescence of dormant disseminated cancer cells (DCC) is crucial for addressing metastatic progression. Infection with respiratory viruses (e.g. influenza or...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: dd9d9d44-bdf5-5a89-8e03-899c74b6b51e
DOI: 10.21203/rs.3.rs-4210090/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Respiratory viral infection promotes the awakening and outgrowth of dormant metastatic breast cancer cells in lungsDOI 10.21203/rs.3.rs-4210090/v1Read

The force awakens: metastatic dormant cancer cellsSemantic proximity Read

Epigenetic plasticity in metastatic dormancy: mechanisms and therapeutic implicationsSemantic proximity Read

Decoding cancer dormancy: integrative genomic, phenotypic and live-cell imaging analysis to reveal the hidden cancer cell reservoir.Semantic proximity Read

Breast cancer progression and metastasis to lymph nodes reveals cancer cell plasticity and MHC class II-mediated immune regulationSemantic proximity Read

The breast cancer pro-metastatic phenotype requires concomitant hyper-activation of ECM remodeling and dsRNA-IFN1 signaling in rare clone cellsSemantic proximity Read

Inflammation awakens dormant cancer cells by modulating the epithelial-mesenchymal phenotypic state.Semantic proximity Read

Decoding the adaptive survival mechanisms of breast cancer dormancySemantic proximity Read

Disseminated breast cancer cells acquire a highly malignant and aggressive metastatic phenotype during metastatic latency in the bone.Semantic proximity Read

Gene expression predicts dormant metastatic breast cancer cell phenotype.Semantic proximity Read

Differential Adaptation and Remodeling of the Tumor Microenvironment in Breast Cancer Cells During the Stages of Brain MetastasisSemantic proximity Read

Emerging Topics on Disseminated Cancer Cell Dormancy and the Paradigm of MetastasisSemantic proximity Read

Resident memory T cells in tumor-distant tissues fortify against metastasis formationSemantic proximity Read