Decoding cancer dormancy: integrative genomic, phenotypic and live-cell imaging analysis to reveal the hidden cancer cell reservoir.

Abstract excerpt

Metastases represent one of the hardest obstacles in cancer treatment, accounting for many cancer-related deaths. Understanding the mechanisms that drive disease progression is essential to improve patient outcomes and develop more effective therapeutic strategies. This phenomenon appears to be elicited by dormant cancer cells (DCCs), which can persist undetected for extended periods of time, entering a...

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