Article
Gene expression predicts dormant metastatic breast cancer cell phenotype.
Breast cancer research : BCR - 29 Jan 2022
Ren Qihao, Khoo Weng Hua, Corr Alexander P, Phan Tri Giang, Croucher Peter I, Stewart Sheila A
Abstract excerpt
BACKGROUND: Breast cancer can recur months to decades after an initial diagnosis and treatment. The mechanisms that control tumor cell dormancy remain poorly understood, making it difficult to predict which patients will recur and thus benefit from more rigorous screening and treatments. Unfortunately, the extreme rarity of dormant DTCs has been a major obstacle to their study. METHODS: To overcome this...
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