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CRISPR–Cas9 applications in T cells and adoptive T cell therapies

12 Apr 2024

Abstract excerpt

T cell immunity is central to contemporary cancer and autoimmune therapies, encompassing immune checkpoint blockade and adoptive T cell therapies. Their diverse characteristics can be reprogrammed by different immune challenges dependent on antigen stimulation levels, metabolic conditions, and the degree of inflammation. T cell-based therapeutic strategies are gaining widespread adoption in oncology and treating...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38609863
DOI: 10.1186/s11658-024-00561-1

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