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CRISPR-Based Tools in Immunity

30 Jan 2019

Abstract excerpt

CRISPR technology has opened a new era of genome interrogation and genome engineering. Discovered in bacteria, where it protects against bacteriophage by cleaving foreign nucleic acid sequences, the CRISPR system has been repurposed as an adaptable tool for genome editing and multiple other applications. CRISPR's ease of use, precision, and versatility have led to its widespread adoption, accelerating biomedical...

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PMID: 30698999
DOI: 10.1146/annurev-immunol-042718-041522

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