Article

Population variation of miRNAs and isomiRs and their impact on human immunity to infection

2020-01-31

Abstract excerpt

<h4>ABSTRACT</h4> MicroRNAs (miRNAs) are key epigenetic regulators of the immune system, yet their variation and contribution to intra- and inter-population differences in immune responses is poorly characterized. Here, we generated 977 miRNA-sequencing profiles from primary monocytes, from individuals of African and European ancestry, following activation of three TLR pathways (TLR4, TLR1/2 and TLR7/8) or infect...

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Literature Corpus work: dd5e6f96-34c3-5b60-b9e3-cbd4e42bf0e5
DOI: 10.1101/2020.01.31.928580

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