Article

Decoding morphogen patterning of human neural organoids with a multiplexed single-cell transcriptomic screen

2024-02-08

Abstract excerpt

Morphogens, secreted signalling molecules that direct cell fate and tissue development, are used to direct neuroepithelial progenitors towards discrete regional identities across the central nervous system. Neural tissues derived from pluripotent stem cells in vitro (neural organoids) provide new models for studying neural regionalization, however, we lack a comprehensive survey of how the developing human neuroep...

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Literature Corpus work: 311a8078-3cdd-5342-98fc-65bb758131d7
DOI: 10.1101/2024.02.08.579413

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