Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human Pluripotent Stem Cell Mechanobiology: Manipulating the Biophysical Microenvironment for Regenerative Medicine and Tissue Engineering Applications

20 Jul 2015

Abstract excerpt

A stem cell in its microenvironment is subjected to a myriad of soluble chemical cues and mechanical forces that act in concert to orchestrate cell fate. Intuitively, many of these soluble and biophysical factors have been the focus of intense study to successfully influence and direct cell differentiation in vitro. Human pluripotent stem cells (hPSCs) have been of considerable interest in these studies due to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3D Printing in Biomedical Research
Share to Pluripotent Stem Cells Research
Share to Tissue Engineering and Regenerative Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26189759
DOI: 10.1002/stem.2105

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human Pluripotent Stem Cell Mechanobiology: Manipulating the Biophysical Microenvironment for Regenerative Medicine and Tissue Engineering ApplicationsPMID 26189759Read ↗

Modulation of human mesenchymal and pluripotent stem cell behavior using biophysical and biochemical cues: A reviewSemantic proximity Read ↗

Modulating the biochemical and biophysical culture environment to enhance osteogenic differentiation and maturation of human pluripotent stem cell-derived mesenchymal progenitorsSemantic proximity Read ↗

Physical cues of cell culture materials lead the direction of differentiation lineages of pluripotent stem cellsSemantic proximity Read ↗

Soft culture substrates favor stem-like cellular phenotype and facilitate reprogramming of human mesenchymal stem/stromal cells (hMSCs) through mechanotransductionSemantic proximity Read ↗

Biomechanical cues as master regulators of hematopoietic stem cell fateSemantic proximity Read ↗

Biophysical subsets of embryonic stem cells display distinct phenotypic and morphological signatures.Semantic proximity Read ↗

Actuation Enhances Patterning in Human Neural Tube OrganoidsSemantic proximity Read ↗

Mechanobiology: A landscape for reinterpreting stem cell heterogeneity and regenerative potential in diseased tissuesSemantic proximity Read ↗

Response of Pluripotent Stem Cells to Environmental Stress and Its Application for Directed DifferentiationSemantic proximity Read ↗

Optimizing the osteogenic potential of adult stem cells for skeletal regenerationSemantic proximity Read ↗

Concise Review: Growing Hearts in the Right Place: On the Design of Biomimetic Materials for Cardiac Stem Cell DifferentiationSemantic proximity Read ↗

Extracellular Matrix Regulation of Stem Cell BehaviorSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.