Article

Polygenic associations with phenotypic classes across the psychosis-affective spectrum

2026-07-14

Abstract excerpt

<h4>Introduction</h4> Limitations of current classifications of schizophrenia, schizoaffective disorder, and bipolar disorder are evident from their overlapping symptoms, aetiologies, treatments, and outcomes, and present a barrier to novel treatment discovery. Alternative conceptualisations are needed to address nosological validity, align diagnosis to aetiology, and improve prognostication and treatment choice....

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Literature Corpus work: dcf81d47-3239-5f65-85d5-4d44eac455bd
DOI: 10.64898/2026.07.10.26357470

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