Article

Multitrait genetic-phenotype associations to connect disease variants and biological mechanisms

2020-06-28

Abstract excerpt

<h4>Background</h4> Genome-wide association studies (GWAS) uncovered a wealth of associations between common variants and human phenotypes. These results, widely shared across the scientific community as summary statistics, fostered a flurry of secondary analysis: heritability and genetic correlation assessment, pleiotropy characterization and multitrait association test. Amongst these secondary analyses, a risin...

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Literature Corpus work: dceb3faa-fd27-53c2-9d4c-dfa6b7c5af4c
DOI: 10.1101/2020.06.26.172999

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