Multitrait transcriptome-wide association study (TWAS) tests.

doi:10.1002/gepi.22391

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Article

Multitrait transcriptome-wide association study (TWAS) tests.

Genetic epidemiology - 1 Sept 2021

Feng Helian, Mancuso Nicholas, Pasaniuc Bogdan, Kraft Peter

Abstract excerpt

Multitrait tests can improve power to detect associations between individual single-nucleotide polymorphisms (SNPs) and several related traits. Here, we develop methods for multi-SNP transcriptome-wide association (TWAS) tests to test the association between predicted gene expression levels and multiple phenotypes. We show that the correlation in TWAS test statistics for multiple phenotypes has the same form as...

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PMID: 34082479
DOI: 10.1002/gepi.22391

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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