Article

Genetic and environmental correlations between complex phenotypes differ by race/ethnicity and sex

2021-09-10

Abstract excerpt

We developed novel closed-form estimators of genetic and environmental correlation coefficients. We applied them to estimate over 4,000 genetic and environmental correlations between multiple phenotypes in a diverse sample from the Trans-Omics in Precision Medicine (TOPMed) program. We found substantial differences in heritabilities, genetic, and environmental correlations of multiple phenotypes and phenotype-pair...

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Literature Corpus work: dab5d7bd-9b8e-5e23-afb7-1fe95ab1bf2c
DOI: 10.1101/2021.09.05.21263126

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