Article

The Effect of Mechanical Stimuli on the Phenotypic Plasticity of Induced Pluripotent Stem Cell-Derived Vascular Smooth Muscle Cells in a 3D Hydrogel

2023-09-13

Abstract excerpt

<h4>Introduction</h4> Vascular smooth muscle cells (VSMCs) play a pivotal role in vascular homeostasis, with dysregulation leading to vascular complications. Human induced pluripotent stem cell (hiPSC)-derived VSMCs offer prospects for personalized disease modeling and regenerative strategies. Current research lacks comparative studies on the impact of 3D substrate properties under cyclic strain on phenotype adap...

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Literature Corpus work: dc8392da-8baa-5fba-a135-98aa2eec846c
DOI: 10.1101/2023.09.11.557280

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