Article

Engineering a Matrix-Preserving Vascular dECM Platform with Tunable Stiffness for <i>In Vitro</i> Vascular Remodeling

2026-05-13

Abstract excerpt

<h4>ABSTRACT</h4> Pathologic arterial stiffening is a hallmark of vascular disease that contributes to maladaptive vascular remodeling and neointimal hyperplasia through vascular smooth muscle cell (VSMC) phenotypic switching. Yet, because vascular disease progression is governed by both biomechanical and extracellular matrix (ECM) alterations, existing in vitro models often fail to recapitulate the full complex...

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Literature Corpus work: c12fb87a-4641-5a1a-9692-20a968f396e3
DOI: 10.64898/2026.05.09.724001

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