Article

Single-cell atlas of tumor clonal evolution in liver cancer

2020-08-19

Abstract excerpt

<h4>SUMMARY</h4> Tumor evolution is a key feature of tumorigenesis and plays a pivotal role in driving intratumor heterogeneity, treatment failure and patients’ prognosis. Here we performed single-cell transcriptome profiling of 46 primary liver cancers from 37 patients enrolled for interventional studies. We surveyed the landscape of ~57,000 malignant and non-malignant cells and determined tumor cell clonality b...

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Literature Corpus work: dc795b07-9c18-5daf-a69b-933d55f1cb8b
DOI: 10.1101/2020.08.18.254748

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