Article

Decoding the effect of fibroblast heterogeneity on prognosis and drug resistance in high-grade serous ovarian cancer through tumor evolution analysis

2024-08-05

Abstract excerpt

<title>Abstract</title> <p>Tumor heterogeneity is associated with poor prognosis and drug resistance, leading to therapeutic failure. Here, we used tumor evolution analysis to determine the intra- and intertumoral heterogeneity of high-grade serous ovarian cancer (HGSOC) and analyze the correlation between tumor heterogeneity and prognosis, as well as chemotherapy response, through single-cell and spatial transcr...

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Literature Corpus work: 7d1735f1-1f59-5c1e-8a4f-1be7d2d77b3a
DOI: 10.21203/rs.3.rs-4827560/v1

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