Article

Decoding the impact of fibroblast heterogeneity on prognosis and drug resistance in high-grade serous ovarian cancer through tumor evolution analysis

2024-06-12

Abstract excerpt

<h4>Background: </h4> Tumor heterogeneity is associated with poor prognosis and drug resistance, leading to therapeutic failure. Here, we aim to utilize tumor evolution analysis to decode the intra- and inter-tumoral heterogeneity of high-grade serous ovarian cancer (HGSOC), unraveling the correlation between tumor heterogeneity and prognosis as well as chemotherapy response through single-cell and spatial transcr...

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Literature Corpus work: 0d619ad3-2d07-5e77-802d-0cd174a09478
DOI: 10.1101/2024.06.11.24308797

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