Article

Peripheral CB1R Blockade Suppresses AKI-to-CKD Maladaptive Repair

2026-08-05

Abstract excerpt

<h4>Background</h4> Acute kidney injury (AKI) frequently progresses to chronic kidney disease (CKD), yet mechanisms governing this transition remain poorly understood. The endocannabinoid system (ECS), particularly cannabinoid-1 receptor (CB1R), regulates inflammation and metabolism in various organs, but its role in post-AKI maladaptive repair is less established. <h4>Methods</h4> We analyzed CB1R expression in...

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Literature Corpus work: dbcf7c58-612d-58e8-bdb1-a0c3cb8f553a
DOI: 10.64898/2026.07.31.741993

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