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The Protective Role of Intermedin in Contrast-Induced Acute Kidney Injury: Enhancing Peritubular Capillary Endothelial Cell Adhesion and Integrity through the cAMP/Rac1 Pathway

2024-08-27

Abstract excerpt

<h4>Background: </h4> Contrast-induced acute kidney injury (CIAKI) is a common complication in hospital-acquired renal conditions, yet its pathogenesis remains unclear and effective treatments are limited. Intermedin (IMD), a peptide related to the calcitonin gene, exhibits vasodilatory and endothelial barrier-stabilizing effects via the calcitonin receptor-like receptor (CLR). However, the potential of IMD in mit...

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Literature Corpus work
b0ce6eb3-8743-5770-bd51-ed65a84a35b1
DOI
10.20944/preprints202408.1905.v1
Open publication

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The Protective Role of Intermedin in Contrast-Induced Acute Kidney Injury: Enhancing Peritubular Capillary Endothelial Cell Adhesion and Integrity through the cAMP/Rac1 PathwayDOI 10.20944/preprints202408.1905.v1
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