Article
Cannabinoid CB1 receptor expression in relation to visceral adipose depots, endocannabinoid levels, microvascular damage, and the presence of the Cnr1 A3813G variant in humans.
Metabolism: clinical and experimental - 1 May 2010
Bordicchia Marica, Battistoni Ilaria, Mancinelli Lucia, Giannini Elena, Refi Giada, Minardi Daniele, Muzzonigro Giovanni, Mazzucchelli Roberta, Montironi Rodolfo, Piscitelli Fabiana, Petrosino Stefania, Dessì-Fulgheri Paolo, Rappelli Alessandro, Di Marzo Vincenzo, Sarzani Riccardo
Abstract excerpt
Dysregulation of the endocannabinoid system in the visceral adipose tissue (VAT) is associated with metabolic and cardiovascular complications of obesity. We studied perirenal VAT CB1 receptor expression in relation to anthropometry, VAT area and endocannabinoid levels, kidney microvascular damage (MVDa), and the presence of the CB1 gene A3813G variant, the frequency of which was also evaluated in a large...
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