Hypertension and kidneys: unraveling complex molecular mechanisms underlying hypertensive renal damage.

doi:10.1038/jhh.2013.55

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Article

Hypertension and kidneys: unraveling complex molecular mechanisms underlying hypertensive renal damage.

Journal of human hypertension - 1 Feb 2014

Mennuni S, Rubattu S, Pierelli G, Tocci G, Fofi C, Volpe M

Abstract excerpt

Kidney damage represents a frequent event in the course of hypertension, ranging from a benign to a malignant form of nephropathy depending on several factors, that is, individual susceptibility, degree of hypertension, type of etiology and underlying kidney disease. Multiple mechanisms are involved in determination of kidney glomerular, tubular and interstitial injuries in hypertension. The present review...

Topics

Animals
Antihypertensive Agents
Blood Pressure
Endothelium, Vascular
Genetic Predisposition to Disease
Humans
Hypertension
Inflammation Mediators
Kidney
Kidney Diseases
Oxidative Stress
Prognosis
Renin-Angiotensin System
Risk Factors
Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 23803592
DOI: 10.1038/jhh.2013.55

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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