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Article

Multi-omics characterization of human kidneys identifies cPLA2-arachidonic acid metabolism as a potential driver of inflammation

2022-04-07

Abstract excerpt

<title>Abstract</title> <p>The limited availability of human kidney biopsies to study acute kidney injury (AKI) has restricted the development of effective therapies for this condition. Here, we validate the use of deceased transplant organ donor kidneys to study human AKI and characterized the multi-omics and immune landscape of human AKI kidneys. We demonstrate that changes in kidney injury and inflammatory mar...

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Literature Corpus work
25c6ff7f-9b67-5e52-b3fc-3243d68ca822
DOI
10.21203/rs.3.rs-1461691/v1
Open publication

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Multi-omics characterization of human kidneys identifies cPLA2-arachidonic acid metabolism as a potential driver of inflammationDOI 10.21203/rs.3.rs-1461691/v1
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