Article

Inflammation-mediated Upregulation of VCAM-1 but not KIM-1 during Acute Kidney Injury to Chronic Kidney Disease Transition

2022-09-17

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Patients with acute kidney injury (AKI) have higher risks of developing chronic kidney disease (CKD). The basis for the AKI-to-CKD transition remains poorly understood, but studies in animal models suggest a linkage between the inflammatory response to injury and subsequent nephron loss and interstitial fibrosis. The proximal tubule is the primary venue of injury and progres...

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Literature Corpus work: 07b260dc-f3e7-5efa-8b76-0f2d56065a7f
DOI: 10.1101/2022.09.15.508151

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