Article

APP <sup>NL-F</sup> knock-in Alzheimer’s Disease model mice reveal etiological convergence of aging and amyloidosis

2026-01-31

Abstract excerpt

Alzheimer’s disease (AD) is the leading cause of dementia worldwide, with a steadily increasing prevalence. Despite the advent of some plaque-degrading therapies, early intervention strategies are still suboptimal, largely due to an incomplete understanding of how early pathological events of amyloid-β (Aβ) plaque deposition entail or accompany the neuroinflammatory processes that ensue. The APP NL-F mouse line i...

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Literature Corpus work: dbbe8286-24b4-5a23-8123-57dc73dc6cb4
DOI: 10.64898/2026.01.28.702259

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