Article
S100A8-enriched microglia populate the brain of tau-seeded and accelerated aging mice
2023-11-13
Abstract excerpt
Long considered to fluctuate between pro- and anti-inflammatory states, it has now become evident that microglia occupy a variegated phenotypic landscape with relevance to aging and neurodegeneration. However, whether specific microglial subsets converge in or contribute to both processes that eventually affect brain function is less clear. To investigate this, we analyzed microglial heterogeneity in a tauopathy m...
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Identifiers and source
- Literature Corpus work
- 400a68a8-03d0-5a8d-9a97-24f76a3e8f25
- DOI
- 10.1101/2023.11.10.566543