Article
Mind the viscous modulus: The mechanotransductive response to the viscous nature of isoelastic matrices regulates stem cell chondrogenesis
2023-03-06
Abstract excerpt
The design of hydrogels as mimetics of tissues’ matrices typically disregards the viscous nature of native tissues and focuses only on their elastic properties. In the case of stem cell chondrogenesis, this has led to contradictory results, likely due to unreported changes of the matrices’ viscous modulus. Here, by employing isoelastic matrices with a Young’s modulus of ~12 kPa, we demonstrate that variations in v...
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Identifiers and source
- Literature Corpus work
- dba56923-6fb0-5968-b7a4-b0c11a909bbd
- DOI
- 10.1101/2023.03.06.530938