Article
Mesenchymal morphogenesis of embryonic stem cells dynamically modulates the biophysical microtissue niche.
Scientific reports - 6 Mar 2014
Kinney Melissa A, Saeed Rabbia, McDevitt Todd C
Abstract excerpt
Stem cell fate and function are dynamically modulated by the interdependent relationships between biochemical and biophysical signals constituting the local 3D microenvironment. While approaches to recapitulate the stem cell niche have been explored for directing stem cell differentiation, a quantitative relationship between embryonic stem cell (ESC) morphogenesis and intrinsic biophysical cues within...
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