Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Solution viscosity regulates chondrocyte proliferation and phenotype during 3D culture.

Journal of materials chemistry. B - 11 Dec 2019

Lee Kyubae, Chen Yazhou, Li Xiaomeng, Wang Yongtao, Kawazoe Naoki, Yang Yingnan, Chen Guoping

Abstract excerpt

Cells are surrounded by an extracellular matrix (ECM), which controls cellular functions through biological or physicochemical cues. In particular, cartilage tissues have abundant ECM that is viscoelastic and provides the necessary signals for the maintenance of chondrocyte activity and metabolism. The influence of ECM stiffness on chondrocyte functions has been broadly investigated using elastic hydrogels....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cattle
Share to Cell Culture Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Proliferation

Share to Chondrocytes

Share to Culture Media

Share to Extracellular Matrix

Share to Gelatin

Share to Viscosity

Source

Identifiers

PMID: 31755881
DOI: 10.1039/c9tb02204j

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Solution viscosity regulates chondrocyte proliferation and phenotype during 3D culture.PMID 31755881Read ↗

Mind the viscous modulus: The mechanotransductive response to the viscous nature of isoelastic matrices regulates stem cell chondrogenesisSemantic proximity Read ↗

Alteration of 3d Matrix Stiffness Regulates Viscoelasticity of Human Mesenchymal Stem CellsSemantic proximity Read ↗

Effects of biophysical cues of 3D hydrogels on mesenchymal stem cells differentiation.Semantic proximity Read ↗

Mesenchymal morphogenesis of embryonic stem cells dynamically modulates the biophysical microtissue niche.Semantic proximity Read ↗

Matrix stress-relaxation and stiffness modulate oligodendrocyte differentiationSemantic proximity Read ↗

Hydrogel viscoelasticity regulates human monocyte-derived macrophage morphology and phenotype in 2D culture.Semantic proximity Read ↗

Interstitial flow upregulates matrix synthesis and attenuates NF-kB signaling in a novel perfusion bioreactor for articular cartilage tissue engineeringSemantic proximity Read ↗

Matrix compliance regulates cellular and nuclear confinement of fibroblasts in tunable protein-based hydrogel microenvironmentsSemantic proximity Read ↗

Substrate stiffness controls the cell cycle of human mesenchymal stem cells via cellular tractionSemantic proximity Read ↗

The role of extracellular matrix viscoelasticity in development and diseaseSemantic proximity Read ↗

The Impact of the Local Mechanical Environment on Cell Shape and Chondrogenesis of Mesenchymal Stromal Cells in 3D Biomimetic Composite MaterialsSemantic proximity Read ↗

Effects of substrate stiffness on the biological behavior of human umbilical vein endothelial cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.