Article
Collagen Scaffold Viscoelasticity Regulates Muscle Cell Phenotype.
Advanced healthcare materials - 1 Feb 2026
Roloson Emily B, Jung Wei-Hung, McNamara Stephanie L, Van Stone Catherine L, Lafuente-Gómez Nuria, Morgan Duncan M, Gibbs Rebecca M, Rubin Lee L, Duda Georg N, Mooney David J
Abstract excerpt
Current biomaterial strategies are typically unable to return skeletal muscle to pre-injury function following damage, resulting in permanent loss of muscle function. Recently, there has been a growing appreciation for the role of matrix viscoelasticity in regenerative processes, and here we address the hypothesis that changes in matrix viscoelasticity regulate muscle cell function. Using norbornene-modified type...
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