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Article

Effects of biophysical cues of 3D hydrogels on mesenchymal stem cells differentiation.

Journal of cellular physiology - 1 Apr 2021

Guo Yutong, Du Shufang, Quan Shuqi, Jiang Fulin, Yang Cai, Li Juan

Abstract excerpt

For stem cell research, three-dimensional (3D) hydrogels are increasingly recognized as more physiological systems than two-dimensional culture plates due to bidirectional and 3D interaction of stem cells and surrounding matrix. Among various stem cells, mesenchymal stem cells (MSCs) are one of the most widely applied from bench to bedside. In 3D hydrogels, MSCs are allowed to actively remodel the surrounding...

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PMID: 32885847
DOI: 10.1002/jcp.30042

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