Article

STING is a key driver of Japanese encephalitis virus induced inflammatory response

2025-06-11

Abstract excerpt

Interferon (IFN) and inflammation are the key early defence mechanisms that combat pathogen infection. The cytosolic DNA sensor cGAS activates immune signaling via the stimulator of interferon genes (STING) protein. Emerging evidence suggests crosstalk between innate immune DNA and RNA sensing, implicating a role of STING protein in RNA virus infection. This study characterizes STING in the context of Japanese enc...

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Literature Corpus work: db5ca01e-86b2-5aab-94aa-1a8610c2170d
DOI: 10.1101/2025.06.11.659027

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