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Article

The regulation of cGAS-STING signaling by RNA virus-derived components

1 May 2024

Abstract excerpt

The Cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) serves as a key innate immune signaling axis involved in the regulation of various human diseases. It has been found that cGAS-STING pathway can recognize a variety of cytosolic double-stranded DNA (dsDNA), contributing to cause a robust type I interferon response thereby affecting the occurrence and progression of viral infection....

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PMID: 38693578
DOI: 10.1186/s12985-024-02359-1

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