Article

HUNTINGTON DISEASE ALTERS THE PATTERNING OF NEOCORTICAL AREA IN MICE

2026-05-14

Abstract excerpt

<h4>Background</h4> Huntington disease (HD) is a neurological disorder caused by an aberrant CAG expansion in the HTT gene, producing a mutant protein (mHTT). Although HD is classically characterized by adult-onset cortical and striatal degeneration, accumulating evidence suggests that altered cortical development may also contribute to disease pathogenesis. <h4>Objective</h4> We sought to investigate the impa...

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Literature Corpus work: db075beb-b97f-5073-bd30-8eb45ab777a1
DOI: 10.64898/2026.05.12.724482

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