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Article

Expression of normal and mutant huntingtin in the developing brain.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Sept 1996

Bhide P G, Day M, Sapp E, Schwarz C, Sheth A, Kim J, Young A B, Penney J, Golden J, Aronin N, DiFiglia M

Abstract excerpt

Huntington's disease (HD) is caused by a genetic mutation that results in a polyglutamine expansion in huntingtin. The time course of neuronal loss in the HD striatum and other affected brain regions before the onset of symptoms is unknown. To determine the potential influence of huntingtin on brain development, we examined its expression in the developing mouse and in human control and HD brain. By Western blot,...

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Identifiers

PMID: 8757264
PMCID: PMC6578889

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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