Article

Fructose utilization by GM-CSF-differentiated macrophages aggravates autoimmune inflammation <i>via</i> MG-derived AGE–RAGE signaling

2026-01-28

Abstract excerpt

<h4>ABSTRACT</h4> Excessive fructose intake is increasingly associated with metabolic and inflammatory pathologies; however, the direct impact of fructose metabolism on immune cell function remains insufficiently understood. Here, we demonstrate that GM-CSF–differentiated macrophages markedly upregulate the fructose-specific transporter GLUT5, enabling efficient fructose utilization through two complementary meta...

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Literature Corpus work: dacba147-8fd4-5542-8b6f-a67b8c120f28
DOI: 10.64898/2026.01.26.701899

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Fructose utilization by GM-CSF-differentiated macrophages aggravates autoimmune inflammation <i>via</i> MG-derived AGE–RAGE signalingDOI 10.64898/2026.01.26.701899Read

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