Article

Multiomics reveals age-dependent metabolic reprogramming of macrophages by wound bed niche secreted signals

2024-11-03

Abstract excerpt

<h4>Summary</h4> The cellular metabolism of macrophages depends on tissue niches and can control macrophage inflammatory or resolving phenotypes. Yet, the identity of signals within tissue niches that control macrophage metabolism is not well understood. Here, using single-cell RNA sequencing of macrophages in early mouse wounds, we find that, rather than gene expression of canonical inflammatory or resolving pol...

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Literature Corpus work: 45f4c8ab-42ae-5c9c-88ba-e0a2d4423a6d
DOI: 10.1101/2024.10.30.621159

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