Article

A Comprehensive Epithelial Tubo-Ovarian Cancer Risk Prediction Model Incorporating Genetic and Epidemiological Risk Factors

2020-12-07

Abstract excerpt

<h4>Background</h4> Epithelial tubo-ovarian cancer (EOC) has high mortality partly due to late diagnosis. Prevention is available but may be associated with adverse effects. A multifactorial risk model based on known genetic and epidemiological risk factors (RFs) for EOC can help identify females at higher risk who could benefit from targeted screening and prevention. <h4>Methods</h4> We developed a multifactorial...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: da95e69b-7646-5042-a814-95533449abe8
DOI: 10.1101/2020.12.04.20244046

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A Comprehensive Epithelial Tubo-Ovarian Cancer Risk Prediction Model Incorporating Genetic and Epidemiological Risk FactorsDOI 10.1101/2020.12.04.20244046Read

Comprehensive epithelial tubo-ovarian cancer risk prediction model incorporating genetic and epidemiological risk factors.Semantic proximity Read

Validation of the BOADICEA model for epithelial tubo-ovarian cancer risk prediction in UK Biobank.Semantic proximity Read

Enhancing the BOADICEA cancer risk prediction model to incorporate new data on RAD51C, RAD51D, BARD1 updates to tumour pathology and cancer incidence.Semantic proximity Read

Genetic epidemiology of ovarian cancer and prospects for polygenic risk prediction.Semantic proximity Read

Epithelial ovarian cancer risk: A review of the current genetic landscapeSemantic proximity Read

Enhancing the BOADICEA cancer risk prediction model to incorporate new data on <i>RAD51C, RAD51D, BARD1</i>, updates to tumour pathology and cancer incidencesSemantic proximity Read

Prospective Evaluation of a Breast Cancer Risk Model Integrating Classical Risk Factors and Polygenic Risk in 15 Cohorts from Six CountriesSemantic proximity Read

CanRisk Tool-A Web Interface for the Prediction of Breast and Ovarian Cancer Risk and the Likelihood of Carrying Genetic Pathogenic Variants.Semantic proximity Read

Breast cancer risk models: a comprehensive overview of existing models, validation, and clinical applications.Semantic proximity Read

BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors.Semantic proximity Read

Ovarian and Breast Cancer Risks Associated With Pathogenic Variants in RAD51C and RAD51D.Semantic proximity Read

Management of individuals with heterozygous germline pathogenic variants in RAD51C, RAD51D, and BRIP1: A clinical practice resource of the American College of Medical Genetics and Genomics (ACMG).Semantic proximity Read