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Article

Genetic epidemiology of ovarian cancer and prospects for polygenic risk prediction.

Gynecologic oncology - 1 Dec 2017

Jones Michelle R, Kamara Daniella, Karlan Beth Y, Pharoah Paul D P, Gayther Simon A

Abstract excerpt

Epithelial ovarian cancer (EOC) is a heterogeneous disease with a major heritable component. The different histotypes of invasive disease - high grade serous, clear cell, endometrioid and mucinous - are associated with different underlying genetic susceptibility and epidemiological and lifestyle risk factors, all of which contribute to the different biology and clinical characteristics of each histotype. A...

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Source

Identifiers

PMID: 29054568
DOI: 10.1016/j.ygyno.2017.10.001

Genes

BRCA1
BRCA2
BRIP1
MSH6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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