Article
CanRisk Tool-A Web Interface for the Prediction of Breast and Ovarian Cancer Risk and the Likelihood of Carrying Genetic Pathogenic Variants.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2021
Carver Tim, Hartley Simon, Lee Andrew, Cunningham Alex P, Archer Stephanie, Babb de Villiers Chantal, Roberts Jonathan, Ruston Rod, Walter Fiona M, Tischkowitz Marc, Easton Douglas F, Antoniou Antonis C
Abstract excerpt
BACKGROUND: The CanRisk Tool (https://canrisk.org) is the next-generation web interface for the latest version of the BOADICEA (Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm) state-of-the-art risk model and a forthcoming ovarian cancer risk model. METHODS: The tool captures information on family history, rare pathogenic variants in cancer susceptibility genes, polygenic risk...
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