Article

Distributed Genetic Effects on Human Brain Structure Emerge Across Multiple Spatial Scales

2026-08-21

Abstract excerpt

Genome-wide association studies (GWAS) have identified hundreds of common genetic variants associated with regional brain volumes, enabling the construction of polygenic scores (PGS) that summarize genetic predisposition for variation in specific neuroanatomical traits. To investigate how these genetic influences are exerted spatially throughout the brain, we computed PGS for ten brain volume phenotypes, including...

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Literature Corpus work: 8fb984d6-aeee-5084-bcd5-68160be2e58e
DOI: 10.64898/2026.08.17.745237

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