Article

Multi-trait genome-wide analyses of the brain imaging phenotypes in UK Biobank

2019-09-05

Abstract excerpt

Many genetic variants identified in genome-wide association studies (GWAS) are associated with multiple, sometimes seemingly unrelated traits. This motivates multi-trait association analyses, which have successfully identified novel associated loci for many complex diseases. While appealing, most existing methods focus on analyzing a relatively small number of traits and may yield inflated Type I error rates when...

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Literature Corpus work: d137c54c-06cf-57fd-b803-2ea70516ebd1
DOI: 10.1101/758326

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