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Whole-genome sequencing reveals variant associations with brain imaging phenotypes

2026-01-08

Abstract excerpt

Whole-genome sequencing (WGS) enables comprehensive discovery of genetic variation underlying brain imaging traits beyond the limits of SNP arrays, particularly for rare coding variants with potentially large effects. Here, we integrated WGS data from 45,755 UK Biobank participants with 4,016 derived imaging phenotypes (IDPs) spanning macrostructure (volumes, cortical thickness/area), microstructure (diffusion met...

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Literature Corpus work
259c715d-9ed1-5f5f-81ad-c9642c64b6ec
DOI
10.64898/2026.01.07.697998
Open publication

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Whole-genome sequencing reveals variant associations with brain imaging phenotypesDOI 10.64898/2026.01.07.697998
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