Article
Transcriptome-wide association analysis of 211 neuroimaging traits identifies new genes for brain structures and yields insights into the gene-level pleiotropy with other complex traits
2019-11-15
Abstract excerpt
Structural and microstructural variations of human brain are heritable and highly polygenic traits, with hundreds of associated genes founded in recent genome-wide association studies (GWAS). Using gene expression data, transcriptome-wide association studies (TWAS) can prioritize these GWAS findings and also identify novel gene-trait associations. Here we performed TWAS analysis of 211 structural neuroimaging phen...
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Identifiers and source
- Literature Corpus work
- e1c53ea7-00c5-52a8-b413-b754c1201162
- DOI
- 10.1101/842872