Article

Mosaic Mutations in Blood DNA Sequence Are Associated with Solid Tumor Cancers

2016-07-25

Abstract excerpt

Recent findings in understanding the causal role of blood-detectable somatic protein-truncating DNA variants in leukemia prompt questions about generalizability of such observations for other cancer types. We used exome sequencing to compare 22 different cancer phenotypes from TCGA data (~8,000 samples) with more than 6,000 controls using a case-control study design and demonstrate that mosaic protein truncating v...

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Literature Corpus work: da4c19f0-82ac-5265-a0f6-e6c98de1ede8
DOI: 10.1101/065821

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