Article
The biology and clinical impact of genetic lesions in myeloid malignancies.
Blood - 28 Nov 2013
Lindsley R Coleman, Ebert Benjamin L
Abstract excerpt
A longstanding endeavor to define the genetic lesions that drive myeloid malignances has stimulated a period of remarkable discovery. Enabled by technological advances that have sharply decreased the cost of DNA sequencing, the full compendium of common, recurrent somatic mutations in the coding genome of myeloid malignancies is nearly complete. As the focus of genetic discovery shifts to the noncoding genome,...
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